Harold Aukema PhD

phone: (204) 474-8076
fax:
Current Positions Held

Professor, Department of Human Nutritional Sciences, University of Manitoba
Scientist, Manitoba Institute of Child Health
Investigator, Richardson Centre for Functional Foods and Nutraceuticals
Affiliate Member, Canadian Centre for Agri-Food Research in Health and Medicine

Training, Education & Background

1992 PhD, Nutritional Sciences, University of Guelph
1988 MSc, Nutritional Sciences, University of Guelph
1986 BSc, Animal and Poultry Science, University of Guelph

Major Research Focus & Interests

Fetal programming: Effects of perinatal nutrition on kidneys in models of congenital kidney disease
Dietary recommendations: Physiologic and metabolic basis of dietary recommendations for dietary protein and for omega-3 fatty acids
Renal eicosanoids: Dietary effects on eicosanoids and related enzymes in normal kidneys and diseased kidneys resulting from genetic mutations, diabetes and obesity
Nutrition and the kidney: Effects of dietary components, nutraceuticals and functional foods on normal renal metabolism and prevention of renal disease progression

Supervised Students

Jessay Gopuran, Graduate Student
Naser Ibrahim, Graduate Student
Adriana Mudryj, Graduate Student
Natalie Prairie, Graduate Student
Hong Shi, Graduate Student
Jennifer Wojcik, Graduate Student
Stephanie Caligiuri, Student Research Assistant
Ashleigh Reid, Student Research Assistant

Recent Significant Publications

Pye KM, Wakefield AP, Aukema HM, House JD, Ogborn MR, Weiler HA. A High Mixed Protein Diet Reduces Body Fat without Altering the Mechanical Properties of Bone in Female Rats. J Nutr 139: 2099-2105, 2009.

Fan YY, Zhang Y, Aukema HM, Davidson LA, Zhou L, Callaway E, Tian Y, Weeks BR, Lupton JR, Toyokuni S, Chapkin RS. Pro-apoptotic effects of dietary (n-3) fatty acids are enhanced in colonocytes of SOD2 knockout mice. J Nutr 139:1328-1332, 2009.

Peng CYC, Sankaran D, Ogborn MR, Aukema HM. Dietary soy protein selectively reduces renal prostanoids and cyclooxygenases in polycystic kidney disease. Exp Biol Med 234:737-743, 2009.

Drury B, Warford-Woolgar LJ, Herchak DJ, Bankovic-Calic N, Grow G, Taylor CG, Zahradka P, Ogborn MR, Aukema HM. Dietary trans 10, cis 12 conjugated linoleic acid reduces early glomerular enlargement and elevated renal cyclooxygenase-2 levels in young obese fa/fa Zucker rats. J Nutr 139:285-290, 2009.

Scatliff CE, Bankovic-Calic N, Ogborn MR, Aukema HM. Effects of dietary conjugated linoleic acid in advanced experimental polycystic kidney disease. Nephron Exp Nephrol 110:44-48, 2008.

Ogborn MR, Nitschmann E, Goldberg A, Bankovic-Calic N, Weiler HA, Aukema HM. Dietary conjugated linoleic acid renal benefits and possible toxicity vary with isomer, dose and gender in rat polycystic kidney disease. Lipids 43:783-91, 2008.

Hwang SY, Taylor CG, Zahradka P, Bankovic-Calic N, Ogborn M, Aukema HM. Dietary soy protein reduces early renal disease progression and alters prostanoid production in obese fa/fa Zucker rats. J Nutr Biochem 19:255-262, 2008.

Sankaran D, Bankovic-Calic N, Crow G, Ogborn MR, Aukema HM. Selective COX-2 inhibition markedly slows disease progression and attenuates altered prostanoid production in Han:SPRD-cy rats with inherited kidney disease. Am J Physiol – Renal Physiol 293:F821-30, 2007.

Sankaran D, Bankovic-Calic N, Cahill LE, Peng CYC, Ogborn MR, Aukema HM. Late dietary intervention limits benefits of soy protein or flax oil in experimental polycystic kidney disease. Nephron Exp Nephrol 106:e122-128, 2007.

Sankaran D, Lu J, Ogborn MR, Aukema HM. COX-2 expression in cystic kidneys is dependent on dietary n-3 fatty acid composition. J Nutr Biochem 18:806-812, 2007.

Cahill LE, Peng CYC, Bankovic-Calic N, Sankaran D, Ogborn MR, Aukema HM. Dietary soy protein during pregnancy and lactation in rats with hereditary kidney disease attenuates disease progression in offspring. Br J Nutr 97:77-84, 2007.

Weiler HA, Kovacs H, Nitschmann E, Bankovic-Calic N, Aukema HM, Ogborn MR. Feeding flaxseed oil but not secoisolariciresinol diglucoside results in higher bone mass in healthy rats and rats with kidney disease. Prostaglandins Leuko. Essent. Fatty Acids 76: 269-75, 2007.