MICH Researchers Recent Publications
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Protudjer JL, McGavock JM, Ramsey CD, Sevenhuysen GP, Kozyrskyj AL, Becker AB. |
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J Asthma . 2012 Jun;49(5):496-501. Epub 2012 May 3. |
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PMID: 22554059 [PubMed - in process] |
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ST3GAL3 mutations impair the development of higher cognitive functions.
Hu H, Eggers K, Chen W, Garshasbi M, Motazacker MM, Wrogemann K, Kahrizi K, Tzschach A, Hosseini M, Bahman I, Hucho T, Mühlenhoff M, Gerardy-Schahn R, Najmabadi H, Ropers HH, Kuss AW.
Am J Hum Genet. 89: 407-14 (2011)
Enzyme-replacement therapy in life-threatening hypophosphatasia.
Whyte MP, Greenberg CR, Salman NJ, Bober MB, McAlister WH, Wenkert D, Van Sickle BJ, Simmons JH, Edgar TS, Bauer ML, Hamdan MA, Bishop N, Lutz RE, McGinn M, Craig S, Moore JN, Taylor JW, Cleveland RH, Cranley WR, Lim R, Thacher TD, Mayhew JE, Downs M, Millán JL, Skrinar AM, Crine P, Landy H.
N Engl J Med. 2012 Mar 8;366(10):904-13.
ABCG2 null alleles define the Jr(a-) blood group phenotype.
Zelinski T, Coghlan G, Liu XQ, Reid ME.
Nat Genet. 2012 Jan 15;44(2):131-2. doi: 10.1038/ng.1075.
Nicklas S, Otto A, Wu X, Miller P, Stelzer S, Wen Y, Kuang S, Wrogemann K, Patel K, Ding H, Schwamborn JC.
PLoS One. 2012;7(1):e30445. Epub 2012 Jan 27.
Deep sequencing reveals 50 novel genes for recessive cognitive disorders.
Najmabadi H, Hu H, Garshasbi M, Zemojtel T, Abedini SS, Chen W, Hosseini M, Behjati F, Haas S, Jamali P, Zecha A, Mohseni M, Püttmann L, Vahid LN, Jensen C, Moheb LA, Bienek M, Larti F, Mueller I, Weissmann R, Darvish H, Wrogemann K, Hadavi V, Lipkowitz B, Esmaeeli-Nieh S, Wieczorek D, Kariminejad R, Firouzabadi SG, Cohen M, Fattahi Z, Rost I, Mojahedi F, Hertzberg C, Dehghan A, Rajab A, Banavandi MJ, Hoffer J, Falah M, Musante L, Kalscheuer V, Ullmann R, Kuss AW, Tzschach A, Kahrizi K, Ropers HH.
Nature. 2011 Sep 21;478(7367):57-63. doi: 10.1038/nature10423.
Dr. Trushar R. Patel
Nano-structure of the laminin y-1 short arm reveals an extended and curved
multidomain assembly Matrix Biology, Trushar R. Patel a, Gordon A. Morris b, Daniela Zwolanek c, Douglas R. Keene d, Jianhua Li e, Stephen E. Harding b, Manuel Koch c, Jörg Stetefeld, 2010
Dr. Benedict Albensi
Evidence for the Involvement of Calbindin D28k in the Presenilin 1 Model of Alzheimer’s Disease. G.L. Odero, K. Oikawa*, K.A.C. Glazner, D. Grossman, J. Thiessen, J. Schapansky, N. Ge, M. Martin, G.W. Glazner, and B.C. ALBENSI. Neuroscience 169: 532-543, 2010. *This author is a co-first author.
Strain Specific Differences in Memory and Neuropathology in a Mouse Model of Alzheimer’s Disease. K.A.C. Glazner, G. Odero*, D. Grossman, E. Anema, A. Motnenko, J. Schapansky, D. Oliver, G. Glazner and B.C. ALBENSI. Life Sciences 86: 942-950, 2010. *This author is a co-first author.
Histochemical visualization and diffusion weighted imaging in the TgCRND8 transgenic model of Alzheimer’s disease. J. Thiessen, K.A.C. Glazner, Solmaz Nafez, A. Schellenberg, R. Buist, M. Martin, and B.C. ALBENSI. Brain Structure and Function 215(1): 29-36, 2010.
Dr. Sergio Fanella
Gastric Lavage for the Diagnosis of Pulmonary Blastomycosis in Pediatric Patients Fanella, Sergio MD, FRCPC; Walkty, Andrew MD, FRCPC; Bridger, Natalie MD; Crockett, Maryanne MD, FRCPC; Consunji-Araneta, Raquel MD, FRCPC; Embree, Joanne MD, FRCPC; Karlowsky, James PhD, D(ABMM) The Pediatric Infectious Disease Journal • Volume 29, Number 12, December 2010 (has been e-published ahead of print)
Dr. Bob Schroth
The impact of community workshops on improving early childhood oral health knowledge.MacIntosh AC, Schroth RJ, Edwards J, Harms L, Mellon B, Moffatt M. Pediatr Dent 2010; 32(2): 110-117.
Oral health of Indigenous children and the influence of early childhood caries (ECC) on childhood health and wellbeing. Schroth RJ, Harrison RL, Moffatt ME. Pediatr Clin North Am. 2009; 56(6): 1481-1499.
Dr. Shayne Taback
(multicentre study we participated in)
Designing and implementing sample and data collection for an international genetics study: the Type 1 Diabetes Genetics Consortium (T1DGC). Hilner JE, Perdue LH, Sides EG, Pierce JJ, Wägner AM, Aldrich A, Loth A, Albret L, Wagenknecht LE, Nierras C, Akolkar B; T1DGC. Clin Trials. 2010;7(1 Suppl):S5-S32. Epub 2010 Jul 5.
Dr. Maureen Heamen
Does living on-reserve versus off-reserve make a difference in First Nations birth outcomes in Manitoba, Canada? Heaman, M., Martens, P., Hart, L., Smylie, J., Agnew, E., Simonet, F., Wassimi, S., Fraser, W., & Luo, Z.C. (2010). The Open Women’s Health Journal, 4, 39-45.
North-south gradients in adverse birth outcomes for First Nations and others in Manitoba, Canada Martens, P., Heaman, M., Hart, L., Wilkins, R., Smylie, J., Sassimi, S., Simonet, F., Wu, Y., Fraser, W., & Luo, Z.C. (2010) The Open Women’s Health Journal, 4, 46-54.
Neighbourhood socioeconomic characteristics, birth outcomes and infant mortality among First Nations and non-First Nations in Manitoba, Canada Luo, Z.C., Wilkins, R., Heaman, M., Martens, P., Smylie, J., Hart, L., Wassimi, S., Simonet, F., Wu, Y., & Fraser., W. (2010). . The Open Women’s Health Journal, 4, 55-61.
Individual- and community-level disparities in birth outcomes and infant mortality among First Nations, Inuit and other populations in Quebec. Simonet, F., Wassimi, S., Heaman, M., Smylie, J., Martens, P., Mchugh, N., Labranche, E., Wilkins, R., Fraser, W., & Luo, Z.C. (2010). The Open Women’s Health Journal, 4, 18-24.
Urban living is not associated with better birth and infant outcomes among Inuit and First Nations in Quebec. Simonet, F., Wilkins, R., Heaman, M., Smylie, J., Martens, P., Mchugh, N., Labranche, E., Wassimi, S., Fraser, W., & Luo, Z.C. (2010). The Open Women’s Health Journal,4, 25-31.
Community remoteness, perinatal outcomes and infant mortality among First Nations in Quebec. Wassimi, S., Mchugh, N., Wilkins, R., Heaman, M., Martens, P., Smylie, J., Simonet, F., Fraser, W., & Luo, Z.C. (2010). The Open Women’s Health Journal, 4, 32-38.
Birth outcomes and infant mortality by the degree of rural isolation among First Nations and non-First Nations in Manitoba, Canada. Luo ZC, Wilkins, R., Heaman, M., Martens, P., Smylie, J., Hart, L., Simonet, F., Wassimi, S., Wu, Y., & Fraser, W. (2010). The Journal of Rural Health, 26, 175-181 http://www.cihr-irsc.gc.ca/e/42192.html#a9
Dr. Mojgan Rastegar
Epigenetic control of Hox genes during neurogenesis, development, and disease. Benjamin A. Barber and Mojgan Rastegar Annals of Anatomy 2010 doi:10.1016/j.aanat.2010.07.009
Dr. L. Warda
Developing injury indicators for Canadian children and youth: a modified-Delphi approach. Pike I, Piedt S, Warda L, Yanchar N, Macarthur C, Babul S, Macpherson AK.Inj Prev. 2010 Jun;16(3):154-60
Dr Pawan Sharma
{beta}-Dystroglycan binds caveolin-1 in smooth muscle: a functional role in caveolae distribution and Ca2+ release. Sharma P, Ghavami S, Stelmack GL, McNeill KD, Mutawe MM, Klonisch T, Unruh H, Halayko AJ. Journal of Cell Science August 24, 2010 123: 3061-3070
Dr Andrew Halayko
Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome C.S Ghavami, MM Mutawe, K Hauff, GL Stelmack, D Schaafsma, P Sharma, KD McNeill, T Hynes, SK Kung, H Unruh, T Klonisch, G Hatch, M Los & AJ Halayko. Biochim Biophys Acta 1803:452-467, 2010
The mevalonate cascade as a target to suppress extracellular matrix synthesis by human airway smooth muscle. D Schaafsma, G Dueck, S Ghavami, A Kroeker, K Hauff, FY Xu, KD McNeill, H Unruh, G Hatch & AJ Halayko. Am J Respir Cell Mol Biol May 12 [Epub ahead of print] 2010
Thymic stromal lymphopoietin receptor-mediated IL-6 and CC/CXC chemokines expression in human airway smooth muscle cells: role of MAPKs (ERK1/2, p38, and JNK) and STAT3 pathways L Shan NS Redhu, A Saleh, AJ Halayko, J Chakir & A Soussi Gounni. . J Immunol 184:7134-7143, 2010
B-Dystroglycan binds caveolin-1 in smooth muscle: Functional role in caveolae distribution and Ca2+ release. P Sharma, S Ghavami, GL Stelmack, KD McNeill, MM Mutawe, T Klonisch, H Unruh & AJ Halayko. J Cell Sci Aug 24 (Epub ahead of print) 2010
Epac as a novel effector of airway smooth muscle relaxation SS Roscioni, H Maarsingh, CRS Elzinga, J Schuur, Mark Menzen, AJ Halayko, H Meurs & M Schmidt. . J Cell Mol Med Aug 16 [Epub ahead of print] 2010
Dr. Sam Kung
Emerging applications of lentiviral vectors in dendritic cell-based immunotherapy. Huiming Wang, Liang Zhang and Sam K.P. Kung. Immunotherapy, Sept 2010, in press. [funded by MHRC]
Importin alpha3 interacts with HIV-1 integrase and contributes to HIV-1 nuclear import and replication. Ao Z, Danappa Jayappa K, Wang B, Zheng Y, Kung S, Rassart E, Depping R, Kohler M, Cohen EA, Yao X. J Virol. 2010 Sep;84(17):8650-63. Epub 2010 Jun 16.
Redirecting lentiviral vectors pseudotyped with Sindbis virus-derived envelope proteins to DC-SIGN by modification of N-linked glycans of envelope proteins.Morizono K, Ku A, Xie Y, Harui A, Kung S.K, Roth MD, Lee B, Chen IS. J Virol. 2010 Jul;84(14):6923-34. Epub 2010 May 19
Promoter chromatin remodeling of immediate-early genes is mediated through H3 phosphorylation at either serine 28 or 10 by the MSK1 multi-protein complex. Drobic B, Pérez-Cadahía B, Yu J, Kung SK, Davie JR. Nucleic Acids Res. 2010 Jun;38(10):3196-208. Epub 2010 Feb 3.
Altering the specificity of NK:target cell interactions by genetic manipulation of NK receptor expression on primary mouse NK cells. Jimmy Tran, Sajid Mahmood, James Carlyle and Sam K.P. Kung. Vaccine, 2010, May 14;28(22):3767-72).
Dr Kevin Coombs
Quantitative Proteomic Analyses of Influenza virus-Infected Cultured Human Lung Cells. Kevin M. Coombs*, Alicia Berard, Wanhong Xu, Oleg Krokhin, Xiaobo Meng, John P. Cortens, Darwyn Kobasa, John Wilkins, and Earl G. Brown. Journal of Virology 2010 Vol 84
Dr. Cheryl Rockman Greenberg
Elevated neonatal 3-OH isovalerylcarnitine due to breast mil sources in maternal 3-MCC deficiency. Eichorst J, Alcorn J, Lepage J, Etter M, Antonishyn NA, Fitterer B, Birch DA, Agopsowicz KL, Ruthnum L, Greenberg CR, Lehotay DC. Mol Genet Metab. 2010 Sep; 101(1):84-6.
Carnitine palmitoyltransferase 1A (CPT1A) P479L prevalence in live newborns in Yukon, Northwest Territories, and Nunavut Collins SA, Sinclair G, McIntosh S, Bamforth F, Thompson R, Sobol I, Osborne G, Corriveau A, Santos M, Hanley B, Greenberg CR, Vallance H, Arbour L.. Mol Genet Metab. 2010 Jul 24.
Diagnosis and high incidence of hyperonithinemis-hyperammonemia-homocitrullinemia (HHH) syndrome in northern Saskatchewan. Sokoro AA, Lepage J, Antonishyn N, McDonald R, Rockman-Greenberg C, Irvine J, Lehotay DC. J Inherit Metab Dis. 2010 Jun.
Dr. Richard Keijzer
Thoracoscopic repair in congenital diaphragmatic hernia: patching is safe and reduces the recurrence rate. R. Keijzer, C. van de Ven, J. Vlot, C. Sloots, G.C. Madern, D. Tibboel, K. Bax (2010) J. Ped. Surg. 45(5):953-7.
Guest Editors: The Developmental and Biological Basis of
Pediatric Surgery. R. Keijzer, D. Tibboel (2010) Semin. Pediatr. Surg. 19(3):169-170.
Congenital diaphragmatic hernia. R. Keijzer, P. Puri (2010) Semin. Pediatr. Surg.
19(3):180-5.
Dr. Allan Becker
A novel study design to investigate the early-life origins of asthma in children (SAGE study), Kozyrskyj, A. L., HayGlass, K. T., Sandford, A. J., Paré, P. D., Chan-Yeung, M. and Becker, A. B. (2009), Allergy, 64: 1185–1193.
Lower cortisol levels in children with asthma exposed to recurrent maternal distress from birth, Lisa C. Dreger, Anita L. Kozyrskyj, Kent T. HayGlass, Allan B. Becker, Brian J. MacNeil. (January 2010), The Journal of allergy and clinical immunology, volume 125 issue 1 Pages 116-122
Children’s perceptions of healthful eating and physical activity, J. L.P. Protudjer, G. Marchessault, A. L. Kozyrskyj, A. B. Becker. (Spring 2010), Canadian Journal of Dietetic Practice and Research, Volume 71, issue 1
Dr. Allison Elliot
A novel COMP mutation in an Inuit patient with pseudoachondroplasia and severe short stature Alison M. Elliott, Patricia Bocangel, Martin H. Reed and Cheryl R. Greenberg, Genetics and Molecular Research 9:1785-1790 (2010)
Your name, title of publication, where published, year, volume number, author list.
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Metabolic consequences of hepatic steatosis in overweight and obese adolescents. |
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Wicklow BA, Wittmeier KD, MacIntosh AC, Sellers EA, Ryner L, Serrai H, Dean HJ, McGavock JM. |
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Diabetes Care . 2012 Apr;35(4):905-10. Epub 2012 Feb 22. |
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PMID: 22357180 [PubMed - in process] |
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Hepatic steatosis and low cardiorespiratory fitness in youth with type 2 diabetes. |
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Wittmeier KD, Wicklow BA, MacIntosh AC, Sellers EA, Ryner LN, Serrai H, Gardiner PF, Dean HJ, McGavock JM. |
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Obesity (Silver Spring) . 2012 May;20(5):1034-40. doi: 10.1038/oby.2011.379. Epub 2012 Jan 5. |
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PMID: 22222927 [PubMed - in process] |
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Physical Activity Among Canadian Children on School Days and Non-School Days. |
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Vander Ploeg KA, Wu B, McGavock J, Veugelers PJ. |
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J Phys Act Health . 2011 Dec 27. [Epub ahead of print] |
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PMID: 22207077 [PubMed - as supplied by publisher] |
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McGavock J, Szczepaniak LS, Ayers CR, Abdullah SM, See R, Gore MO, Drazner MH, de Lemos JA, McGuire DK. |
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Diab Vasc Dis Res . 2012 Apr;9(2):131-7. Epub 2011 Nov 8. |
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PMID: 22067724 [PubMed - in process] Free Article |
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Hui A, Back L, Ludwig S, Gardiner P, Sevenhuysen G, Dean H, Sellers E, McGavock J, Morris M, Bruce S, Murray R, Shen GX. |
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BJOG . 2012 Jan;119(1):70-7. doi: 10.1111/j.1471-0528.2011.03184.x. Epub 2011 Oct 21. |
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PMID: 22017967 [PubMed - indexed for MEDLINE] |
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Hay J, Maximova K, Durksen A, Rinaldi R, Torrance B, Ball GD, Majumdar S, Plotnikoff R, Veugelers P, Boule N, Wozny P, McCargar L, Downs S, Lewanczuk R, McGavock JM. Vigorous and not moderate or light physical activity is independently associated with cardiometabolic risk in youths. Arch Ped. Adol. Med. 2012. In Press. Sept 10. Trembath D, Macintosh A, Becker A, Kozyrskyj A, McGavock J. The association between physical activity and arterial stiffness in 12-13 yr olds. Submitted to J. Phys Act Health In press 2012 Wittmeier K, Wicklow B, Griffith A, Sellers E, Dean H, McGavock J. Determinants of successful glycemic control with lifestyle management in youth with type 2 diabetes. Pediatrics & Child Health. 2012; 17:129-132.
